REspond to this discussion by using one reference from peer-reviewed Nursing Journal. Maya Maman Nursing practice is always evolving as new evidence is brought forward in research studies. Evidence-based practice is the use of the best evidence in making clinical decisions based on an integration of the best available evidence, most often from disciplined research, with clinical expertise and patient preferences (Polit & Beck, 2018). Nursing adopts EBP based on appraised and synthesized evidence determined to be relevant depending on clinical expertise and patient preferences. EBP affects clinical practice and results in decisions that are clinically appropriate, cost-effective, and result in positive patient outcomes (Polit & Beck, 2018). EBP is a process that involves asking an answerable clinical question (PICOT), searching for relevant research-based evidence, appraising and synthesizing the evidence, integrating the evidence with clinical expertise and patient preferences, and assessing the effectiveness of actions (Polit & Beck, 2018). The effects must always be assessed for the actual outcome and if adjustments need to be made for a given population or location. According to Polit & Beck (2018), a study by Shah and colleagues (2016) regarding the implementation of 2% chlorhexidine gluconate (CHG) bathing for intensive care unit (ICU) patients to prevent central line-associated bloodstream infections (CLABSI) EBP concluded that this implementation was effective in prevention. Therefore, the nursing practice adopted HCG bathing for all patients with central lines as a proven EBP measure to prevent CLABSI (Polit & Beck, 2018). However, EBP takes an average of 17 years to transfer from evidence to practice, in an effort to reduce translation time, translation and implementation science have been developed to aid in the more timely implementation of new knowledge into practice (Tucker, 2019). The faster the translation time the more beneficial the implementation can be when applied at the bedside.